| 摘要: |
| 有机锗是近30年研究较多的化合物。有机锗的药理作用主要有抗癌、抗炎、抗病毒和免疫调节、抗衰老等;毒理学研究显示有机锗有长期毒性;通过细胞和分子水平研究来阐明有机锗确切作用机理,才能使有机锗更好地为人类键康服务。 |
| 关键词: 锗 药理 毒理 |
| DOI： |
| 投稿时间：1997-12-30修订日期：1998-06-24 |
| 基金项目:国家自然科学基金(93470242)及广西自然科学基金(桂科配9518018)资助项目。 |
|
| Organogermanium Compounds: Pharmocologic and Toxicologic Study |
|
Wang Lu, Mo Ning
|
| (Department of Pharmacology, Guangxi Medical University, 6 Binhulu, Nanning, Guangxi, 530021) |
| Abstract: |
| There have been many studies of organogermanium compounds in the past 30 years.Here review the pharmacological and toxic studies of those compounds.Major pharmacological studies show that organogermanium compounds have the actions of antitumor,antipyretic,antivirus,immune-enhancement and antisenescence etc.Subacute and chronical toxicity tests reveal that long-term intake of organogermanium produces intoxication. Clinical tests confirm the result.A further study of the compounds and better knowlege of their mechanism will help us use these compounds better. |
| Key words: germanium pharmacology toxicology |
