| 引用本文： |
-
谭桂玉,万凌云,张坤,彭凤,韦树根.钩藤的药理作用及临床应用研究进展[J].广西科学,2024,31(1):1-8. [点击复制]
- TAN Guiyu,WAN Lingyun,ZHANG Kun,PENG Feng,WEI Shugen.Research Progress of Pharmacological Action and Clinical Application of Uncaria rhynchophylla[J].Guangxi Sciences,2024,31(1):1-8. [点击复制]
|
|
| 摘要: |
| 钩藤(Uncaria rhynchophylla)是广西区域特色药材品种之一,具有息风定惊、清热平肝的功效,药用历史悠久。钩藤生物碱是钩藤的主要药效成分,对缓解药物成瘾、阿尔茨海默症、高血压等疾病具有显著功效,其方药天麻钩藤饮、复方钩藤降压片等在临床上广泛应用。随着现代医学研究技术的进步,钩藤生物碱及其方药的治病机理正在不断被发现。本文收集近十年钩藤相关研究文献,以钩藤的药效物质为基础,总结钩藤生物碱及其方药的药理研究成果,分析钩藤的临床应用情况,以期为钩藤的新药研发或新应用提供理论借鉴。 |
| 关键词: 钩藤 生物碱 药理 临床应用 |
| DOI：10.13656/j.cnki.gxkx.20240417.001 |
| 投稿时间：2023-10-26修订日期：2023-12-20 |
| 基金项目:国家自然科学基金项目(82360753、81903752),广西自然科学基金项目(2019GXNSFBA185026),广西科技重大专项项目(桂科AA22096021),广西特色药材关键技术研究推广项目(GZKJ2314),广西药用植物园科研基金项目(桂药基202013),广西中药材品质创新研究团队项目(GZKJ2305)资助。 |
|
| Research Progress of Pharmacological Action and Clinical Application of Uncaria rhynchophylla |
|
TAN Guiyu, WAN Lingyun, ZHANG Kun, PENG Feng, WEI Shugen
|
| (Guangxi Key Laboratory of High-Quality Formation and Utilization of Dao-Di Herbs, Guangxi Innovation Center of Breeding Technology for Traditional Chinese Medicine, Guangxi Botanical Garden of Medicinal Plants, Nanning, Guangxi, 530023, China) |
| Abstract: |
| Uncaria rhynchophylla is one of the regional characteristic medicinal materials in Guangxi.It has a long history of medicinal use with the effects of calming the wind,clearing heat and soothing the liver.Uncaria alkaloids are the main effective components of U.rhynchophylla,which have significant effects on relieving drug addiction,Alzheimer's disease,hypertension and other diseases.Its prescriptions,such as Tianma Gouteng Decoction and Compound Gouteng Hypotensive Tablets,are widely used in clinical practice.With the progress of modern medical research technology,the therapeutic mechanism of Uncaria alkaloids and its prescriptions is constantly being discovered.In this article,the related research literatures of U.rhynchophylla in recent ten years were collected.Based on the pharmacodynamic substances of U.rhynchophylla,the pharmacological research results of alkaloids and its prescriptions were summarized,and the clinical application of U.rhynchophylla was analyzed.It is expected to provide theoretical references for the new drug research and development or new application of U.rhynchophylla. |
| Key words: Uncaria rhynchophylla alkaloids pharmacology clinical application |
