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  • 钟定,覃寿明,许辉,张学荣,舒雨雁.新型显色基质法鲎试验对肺部革兰氏阴性菌感染患者的诊断意义[J].广西科学,1996,3(1):60-61,70.    [点击复制]
  • Zhong Ding,Qin Shouming,Xu Hui,Zhang Xuerong,Shu Yuyan.Diagnostic Significance of New Chromogenic Limulus Assay in Patients with Pulmonary GRAM-Negative Bacterial Infection[J].Guangxi Sciences,1996,3(1):60-61,70.   [点击复制]
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新型显色基质法鲎试验对肺部革兰氏阴性菌感染患者的诊断意义
钟定1, 覃寿明1, 许辉1, 张学荣2, 舒雨雁2
0
(1.广西医科大学第一附属医院呼吸内科, 南宁市滨湖路6号 530021;2.广西医科大学蛇毒研究所, 南宁市滨湖路6号 530021)
摘要:
应用新型显色基质法鲎试验(NCLA)测定41例肺部革兰氏阴性(G-)细菌感染患者(G-组);32例肺部非革兰氏阴性细菌感染患者(非G-组);42例无细菌感染的肺病患者(无感染组)的血桨内毒素浓度、并与100例健康者(对照)比较,G-组血浆内毒素水平明显高于对照组,非G-组及无感染组(P均<0.01)。提示新型显色基质法鲎试验有助于对肺部G-细菌感染作出快速、灵敏的诊断。
关键词:  鲎试验  内毒素  肺炎  革兰氏阴性细菌
DOI:
投稿时间:1995-04-08
基金项目:
Diagnostic Significance of New Chromogenic Limulus Assay in Patients with Pulmonary GRAM-Negative Bacterial Infection
Zhong Ding1, Qin Shouming1, Xu Hui1, Zhang Xuerong2, Shu Yuyan2
(1.Department of Respirato ry, The First Affiliated Hospital, Guangxi Medical University, 6 Binhu Road, Nanning, Guangxi, 530021;2.The Snake Venom Rosearch Institute of Guangxi Medical University, 6 Binhu Road, Nanning, Guangxi, 530021)
Abstract:
The concentration of plasma endotoxin in 41 patients with pulmonary gram-negative (G-) bacterial infection (G- group), 32 patients with pulmonary non-G- bacterial infection (non G- group),42 patients without pulmonary bacterial infection (non infection group) were measured by the New Chromogenic Limulus Assay (NCLA), and compared with a control group of 100 normal cases. The concentration of plasma endotoxin in G- group was significantly higher than those of the control group.non G- group and non infection group (all P<0.01). The results showed that NCLA was a quick.sensitive and useful method for the diagnosis of pulmonary G- bacterial infection.
Key words:  limulus assay  endotoxin  pneumonia  gram-negative bacterum

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