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  • 刘布鸣,吴雁,蒋瑾华,钟正贤.紫外一阶导数光谱法测定安定血药浓度[J].广西科学,1996,3(4):15-17.    [点击复制]
  • Liu Buming,Wu Yan,Jiang Jinhua,Zhong Zhengxian.Determination of Diazepam in Blood by UV First Derivative Spectroscopy[J].Guangxi Sciences,1996,3(4):15-17.   [点击复制]
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紫外一阶导数光谱法测定安定血药浓度
刘布鸣, 吴雁, 蒋瑾华, 钟正贤
0
(广西中医药研究所, 南宁市古城路20号 530022)
摘要:
用紫外一阶导数光谱法,消除生物样品的背景干扰,简化分析过程,建立了安定血药浓度的测定方法。
关键词:  紫外一阶导数光谱法  安定  血药浓度
DOI:
投稿时间:1996-08-06
基金项目:
Determination of Diazepam in Blood by UV First Derivative Spectroscopy
Liu Buming, Wu Yan, Jiang Jinhua, Zhong Zhengxian
(Guangxi Institute of Traditional Medical and Pharmaceutical Sciences, 20 Gucheng Road, Nanning, Guangxi, 530022)
Abstract:
The interference from background of biological materials was partially eliminated and analytical process simplified was made by using UV first derivative spectroscopy.This paper reports a study on the method for the determination of diazepam in plasma and determining the original drug in biological fluid after intravenous diazepam by using the method. The determined results were used to study the pharmacokinetics of diazepam.
Key words:  UV first derivative spectroscopy  diazepam  drug concentration in plasma

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