| 引用本文： |
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罗国容,邓卓霖,Stenner F,Sahin U,Pfreundschuh M.肝细胞癌特异抗原的筛选[J].广西科学,1998,5(3):213-214. [点击复制]
- Luo Guorong,Deng Zhuolin,Stenner F,Sahin U,Pfreundschuh M.The Screening of Specific Antigens of Hepatocellular Carcinoma[J].Guangxi Sciences,1998,5(3):213-214. [点击复制]
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| 摘要: |
| 应用重组克隆表达抗原的血清学鉴定技术,从广西肝细胞癌中初步筛选出9个基因克隆,与肝癌患者及其他人血清的反应证明对肝癌有特异性。DNA测序结果与基因库核对,发现其中7个有同源结构;2个为无同源结构的新分子。 |
| 关键词: 肝细胞癌 特异抗原 重组克隆表达抗原的血清学鉴定(SEREX) |
| DOI： |
| 投稿时间：1998-04-28 |
| 基金项目: |
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| The Screening of Specific Antigens of Hepatocellular Carcinoma |
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Luo Guorong, Deng Zhuolin, Stenner F, Sahin U, Pfreundschuh M
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| (Guangxi Medical University, 6 Binhulu, Nanning, Guangxi, 530021) |
| Abstract: |
| "Serological identification of antigens by recombinant expression cloning (SEREX)" technique was used for screening of specific antigens of hepatocelluar carcinoma. Primarily, there were nine of gene clones that had been harvestd from hepatocellular carcinoma tissues from Guangxi, a hight epidemic area in southern China. These antigens reacted to the sera of other persons showed that they were specific for the hepatocellular carcinoma. Analysis of these 9 clonic gene sequences showed that seven of them with and two without homologic structures in gene bank. |
| Key words: Hepatocellular carcinoma specific antigen serological identification of antigens by recombinant expression cloning (SEREX) |
