| 引用本文： |
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钟正贤,陈学芬,周桂芬,袁阿兴.广西产藤茶总黄酮的药理研究[J].广西科学,1999,6(3):216-218. [点击复制]
- Zhong Zhengxian,Chen Xuefen,Zhou Guifen,Yuan Axing.Pharmacological Action of Total Flavone of Ampelopsis grossedentata from Guangxi[J].Guangxi Sciences,1999,6(3):216-218. [点击复制]
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| 摘要: |
| 采用动物实验,探讨广西产藤茶总黄酮(GXTF)对抗血小板聚集,抗血栓,降血脂和抗氧化作用。结果表明,GXTF能明显抑制大鼠体外血小板聚集和体内血栓形成;降低高血脂症模型小鼠血脂和血糖水平;提高D-半乳糖所致小鼠衰老模型血清和肝脏中超氧化物歧化酶(SOD)活性,减少丙二醛(MDA)含量。由此表明GXTF具有抗血小板聚集和血栓形成,降血脂和抗氧化作用。 |
| 关键词: 藤茶 抗血小板聚集 抗血栓形成 降血脂 抗氧化 动物实验 |
| DOI： |
| 投稿时间：1998-11-26 |
| 基金项目: |
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| Pharmacological Action of Total Flavone of Ampelopsis grossedentata from Guangxi |
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Zhong Zhengxian, Chen Xuefen, Zhou Guifen, Yuan Axing
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| (Guangxi Institute of Traditional Medical and Pharmaceutical Sciences, 20-1 Donggelu, Nanning, Guangxi, 530022, China) |
| Abstract: |
| For studying the pharmacological action of total flavone of Ampelopsis grossedentata from Guangxi (GXTF), experimental observation on its antiplatelet aggregation, antithrombus, lipid-lowering and antioxidation was performed using animals experiment. The results showed that GXTF could signicantly inhibite the platelet aggregation in vitro and thrombus formation of rats in vivo, reduce the levels of serum lipid and blood glucose in hyperlipidemia model mice. In addition it also increased the superoxide dismutase(SOD) activity and decreased the malondialdehyde (MDA) content in serum and liver of aging model mice induced by D-galactose. All these suggests that GXTF has effects of anti platelet aggregation, anti-thrombus formation, lipid-lowering and antioxidation. |
| Key words: Ampelopsis grossedentata anti-platelet aggregation anti thrombus formation lipid-lowering antioxidation animal experiment |
