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  • 杨子明,张利,刘金磊,李典鹏,黄仕训.石笔木茶水对小鼠机体的影响[J].广西科学,2020,27(4):413-417.    [点击复制]
  • YANG Ziming,ZHANG Li,LIU Jinlei,LI Dianpeng,HUANG Shixun.Effects of Tutcheria championi Tea on the Body of Mice[J].Guangxi Sciences,2020,27(4):413-417.   [点击复制]
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石笔木茶水对小鼠机体的影响
杨子明, 张利, 刘金磊, 李典鹏, 黄仕训
0
(广西壮族自治区中国科学院广西植物研究所, 广西植物功能物质研究与利用重点实验室, 广西桂林 541006)
摘要:
研究石笔木(Tutcheria championi)茶水对小鼠机体的影响,为石笔木的开发应用提供理论依据。选取72只小鼠分成4组,低、中、高剂量组投喂相应浓度的石笔木茶水,空白对照组投喂蒸馏水,连续投喂90 d。每天观察小鼠的外观、行为、活动、精神状态等,按时记录小鼠饮食量、饮水量以及体重变化。观察结束后,取血及内脏进行常规的血液生化指标测定并计算主要脏器指数。实验结果表明:石笔木茶水各剂量组小鼠未见明显异常反应,饮食量、体重增加量、血糖、血脂、脏器指数以及肝肾功能指标与空白对照组比较均没有显著性差异;石笔木茶水各剂量组饮水量均明显小于空白组饮水量,差异有统计学意义。短时间(90 d)内,持续饮用石笔木茶水对小鼠机体没有显著影响,但会明显减少饮水量。
关键词:  石笔木  茶水  机体  血脂  代谢  小鼠
DOI:10.13656/j.cnki.gxkx.20200924.007
基金项目:国家自然科学基金项目(81960674),广西科技重大专项(桂科AA17204038),广西科学院基本科研业务费项目(2019YJJ1002)和广西植物功能物质研究与利用重点实验室主任基金项目(ZRJJ2018-12,ZRJJ2019-1)资助。
Effects of Tutcheria championi Tea on the Body of Mice
YANG Ziming, ZHANG Li, LIU Jinlei, LI Dianpeng, HUANG Shixun
(1. Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization, Guangxi Institute of Botany, Guangxi Zhuang Autonomous Region and Chinese Academy of Sciences, Guilin, Guangxi, 541006, China)
Abstract:
The study of the effects of Tutcheria championi tea on the body of mice provides a theoretical basis for the development and application of T.championi. 72 mice were selected and divided into 4 groups. The low,medium and high dose groups were fed with the corresponding concentration of T.championi tea,and the blank control group was fed with distilled water for 90 d.The appearance,behavior,activity and mental state of the mice were observed every day,and the changes in diet and water intake and body weight of mice were recorded on time. After the observation,blood and viscera were taken for routine determination of blood biochemical indexes and calculation of main organ index. There was no obvious abnormal reaction in the mice in each dose group of T.championi tea,and there were no significant differences in dietary intake,weight gain,blood glucose,blood lipids,organ index,and liver and kidney function indicators compared with the blank control group. The amount of tea intake in T.championi each dose group was significantly less than that of the blank group,and the difference was statistically significant. For a short period of time (90 d),continuous drinking of T.championi tea had no significant effect on the body of mice,but it could significantly reduce the amount of water intake.
Key words:  Tutcheria championi  tea  body  blood lipids  metabolism  mice

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