新型冠状病毒疫苗潜在不良反应的研究进展

Research Progress on the Adverse Event Following Immunization of COVID-19 Vaccines

关键词:  新型冠状病毒  新冠疫苗  疑似预防接种异常反应  不良反应  大规模疫苗接种  医疗保障

Key words:  Coronavirus Disease-2019  COVID-19 vaccines  adverse event following immunization  adverse reactions  large-scale vaccination  health care

摘要:

新型冠状病毒（Severe Acute Respiratory Syndrome Coronavirus 2，SARS-CoV-2）感染引起的新型冠状病毒肺炎（Coronavirus Disease-2019，COVID-19，简称新冠肺炎）在全球流行暴发，严重威胁人类生命健康，给全球造成了巨大的医疗、经济和社会破坏。在目前缺乏特异性治疗方法的情况下，预防性疫苗是全球新冠肺炎防控最有效的手段，国内外已有17个（其中我国5个）新型冠状病毒疫苗（简称新冠疫苗）获批附条件上市或紧急使用。为了应对大规模疫苗接种潜在的不良反应挑战，本文对全球已投入使用的新冠疫苗的安全性进行总结，分析其潜在的不良反应，提出加强应对新冠疫苗接种不良事件及医疗应急保障的思考。

Abstract:

Coronavirus Disease-2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) outbreak worldwide, which seriously threats human life and health have caused enormous medical, economic and social damage to the world.In the absence of specific therapy at present, the prophylactic vaccine is the most effective method of preventing and controlling COVID-19 in the world.Seventeen COVID-19 vaccines have been approved for conditional listing or emergency use at home and abroad,including 5 in China.In order to cope with the adverse event following immunization (AEFI) of large-scale vaccination,the safety of new coronavirus vaccines in use worldwide was summarized in this article.The adverse event following immunization was analyzed, and some thoughts on strengthening the response to adverse events of new coronavirus vaccination and medical emergency support were also put forward.