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黄艳冰,何其欢,梁永源,甘永霞,潘丽霞,杨登峰.真菌来源含[2.2.2]-环二氮辛烷环系统的异戊烯基吲哚生物碱[J].广西科学,2020,27(1):40-48. [点击复制]
- HUANG Yanbing,HE Qihuan,LIANG Yongyuan,GAN Yongxia,PAN Lixia,YANG Dengfeng.Fungi Origins of the Bicyclo [2.2.2] Diazaoctane Ring System of Prenylated Indole Alkaloids[J].Guangxi Sciences,2020,27(1):40-48. [点击复制]
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| 真菌来源含[2.2.2]-环二氮辛烷环系统的异戊烯基吲哚生物碱 |
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黄艳冰1, 何其欢1, 梁永源1, 甘永霞1, 潘丽霞2, 杨登峰1
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| (1.广西科学院北部湾海洋研究中心, 广西海洋天然产物与组合生物合成化学重点实验室, 广西南宁 530007;2.广西科学院国家非粮生物质能源工程技术研究中心, 非粮生物质酶解国家重点实验室, 广西南宁 530007) |
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| 摘要: |
| 近年来，真菌因其种类繁多、分布广泛，且能够产生大量结构新颖、活性显著的代谢产物而受到广泛关注。本文综述了从真菌中分离得到的含[2.2.2]-环二氮辛烷环系统的异戊烯基吲哚生物碱的结构及生物活性，其中包括malbrancheamides类、brevianamides类、chrysogenamides类、marcfortines类、paraherquamides类、asperparalines类、stephacidins类和notoamides类。真菌来源含[2.2.2]-环二氮辛烷环结构的异戊烯基吲哚生物碱不仅结构奇特，并且表现出多种重要的生物活性，具有潜在的研究和应用价值。 |
| 关键词: 真菌 二酮哌嗪 异戊烯基吲哚生物碱 [2.2.2]-环二氮辛烷环 生物活性 |
| DOI：10.13656/j.cnki.gxkx.20200311.005 |
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| 基金项目:国家自然科学基金项目（31660251，31860245，31960203）和广西自然科学基金项目（2017GXNSFAA198010，2018GXNSFAA138024，2018GXNSFAA281019）资助。 |
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| Fungi Origins of the Bicyclo [2.2.2] Diazaoctane Ring System of Prenylated Indole Alkaloids |
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HUANG Yanbing1, HE Qihuan1, LIANG Yongyuan1, GAN Yongxia1, PAN Lixia2, YANG Dengfeng1
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| (1.Guangxi Key Laboratory of Marine Natural Products and Combinatorial Biosynthesis Chemistry, Beibu Gulf Marine Research Center, Guangxi Academy of Sciences, Nanning, Guangxi, 530007, China;2.National Engineering Research Center for Non-Food Biorefinery, State Key Laboratory of Non-Food Biomass and Enzyme Technology, Guangxi Academy of Sciences, Nanning, Guangxi, 530007, China) |
| Abstract: |
| In recent years,fungi have attracted extensive attention because of their species diversity and wide distribution,which can produce a large number of metabolites with novel structure and significant activity.In this paper,the structure and bioactivity of the bicyclo[2.2.2] diazaoctane ring system of prenylated indole alkaloids from fungi were reviewed,including malbrancheamides,brevianamides,chrysogenamides,marcfortines,paraherquamides,asperparalines,stephacidins,notoamides.This bicyclo[2.2.2] diazaoctane ring system of prenylated indole alkaloids from fungi not only have peculiar structures,but also exhibit a variety of important biological activities,which have potential research and application value. |
| Key words: fungi diketopiperazines prenylated indole alkaloids bicyclo [2.2.2] diazaoctane ring biological activities |
